Physical Properties | | | |
Molecular Weight: 401.466 g/mol | logS: -8.86367 | SlogP: 5.33912 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.04318 | Sterimol/B1: 2.57271 | Sterimol/B2: 4.37322 | Sterimol/B3: 5.72149 |
Sterimol/B4: 7.9352 | Sterimol/L: 19.1862 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 715.416 | Positive charged surface: 460.179 | Negative charged surface: 255.237 | Volume: 391 |
Hydrophobic surface: 568.068 | Hydrophilic surface: 147.348 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |