Physical Properties | | | |
Molecular Weight: 405.458 g/mol | logS: -2.1995 | SlogP: 2.31942 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.137958 | Sterimol/B1: 2.37166 | Sterimol/B2: 4.19307 | Sterimol/B3: 5.01616 |
Sterimol/B4: 8.96086 | Sterimol/L: 17.2158 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 656.532 | Positive charged surface: 458.512 | Negative charged surface: 198.02 | Volume: 384.625 |
Hydrophobic surface: 526.718 | Hydrophilic surface: 129.814 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |