Physical Properties | | | |
Molecular Weight: 413.453 g/mol | logS: -6.12851 | SlogP: 1.93487 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.104947 | Sterimol/B1: 4.02776 | Sterimol/B2: 4.73601 | Sterimol/B3: 4.75542 |
Sterimol/B4: 8.66104 | Sterimol/L: 15.5139 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 697.203 | Positive charged surface: 364.5 | Negative charged surface: 332.702 | Volume: 403.25 |
Hydrophobic surface: 570.393 | Hydrophilic surface: 126.81 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 2 | Acid groups: 2 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |