Physical Properties | | | |
Molecular Weight: 415.704 g/mol | logS: -5.82701 | SlogP: 4.7443 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.039487 | Sterimol/B1: 2.45446 | Sterimol/B2: 3.24601 | Sterimol/B3: 3.89312 |
Sterimol/B4: 8.41688 | Sterimol/L: 17.8471 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 627.319 | Positive charged surface: 339.444 | Negative charged surface: 287.874 | Volume: 349.5 |
Hydrophobic surface: 568.695 | Hydrophilic surface: 58.624 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |