Physical Properties | | | |
Molecular Weight: 455.691 g/mol | logS: -8.19802 | SlogP: 5.9379 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0451712 | Sterimol/B1: 2.57175 | Sterimol/B2: 3.1605 | Sterimol/B3: 5.09094 |
Sterimol/B4: 5.70238 | Sterimol/L: 21.9627 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 657.317 | Positive charged surface: 263.587 | Negative charged surface: 393.73 | Volume: 363.375 |
Hydrophobic surface: 597.92 | Hydrophilic surface: 59.397 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |