Physical Properties | | | |
Molecular Weight: 437.289 g/mol | logS: -7.21833 | SlogP: 5.9193 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.034479 | Sterimol/B1: 2.35192 | Sterimol/B2: 3.13477 | Sterimol/B3: 4.13942 |
Sterimol/B4: 7.18062 | Sterimol/L: 22.0394 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 672.888 | Positive charged surface: 348.026 | Negative charged surface: 324.862 | Volume: 372.875 |
Hydrophobic surface: 634.737 | Hydrophilic surface: 38.151 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |