Physical Properties | | | |
Molecular Weight: 320.481 g/mol | logS: -5.53861 | SlogP: 4.0833 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0692108 | Sterimol/B1: 2.30927 | Sterimol/B2: 2.98894 | Sterimol/B3: 5.09625 |
Sterimol/B4: 6.43328 | Sterimol/L: 17.5174 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 563.522 | Positive charged surface: 337.578 | Negative charged surface: 225.944 | Volume: 302.375 |
Hydrophobic surface: 442.108 | Hydrophilic surface: 121.414 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |