Physical Properties | | | |
Molecular Weight: 397.269 g/mol | logS: -4.15539 | SlogP: 1.6512 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.159973 | Sterimol/B1: 2.67962 | Sterimol/B2: 3.93942 | Sterimol/B3: 3.95931 |
Sterimol/B4: 7.69842 | Sterimol/L: 13.9404 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 590.827 | Positive charged surface: 234.22 | Negative charged surface: 356.607 | Volume: 318.625 |
Hydrophobic surface: 425.2 | Hydrophilic surface: 165.627 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 2 | Basic groups: 0 |
Chiral centers: 1 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |