Physical Properties | | | |
Molecular Weight: 404.388 g/mol | logS: -5.23602 | SlogP: 5.0923 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.124443 | Sterimol/B1: 2.4213 | Sterimol/B2: 3.11122 | Sterimol/B3: 5.33572 |
Sterimol/B4: 8.94235 | Sterimol/L: 15.3952 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 602.272 | Positive charged surface: 322.672 | Negative charged surface: 279.6 | Volume: 351.75 |
Hydrophobic surface: 414.63 | Hydrophilic surface: 187.642 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |