Physical Properties | | | |
Molecular Weight: 319.426 g/mol | logS: -2.37595 | SlogP: -0.2015 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0561953 | Sterimol/B1: 2.09089 | Sterimol/B2: 3.11392 | Sterimol/B3: 4.85336 |
Sterimol/B4: 7.74953 | Sterimol/L: 17.0494 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 606.016 | Positive charged surface: 394.01 | Negative charged surface: 212.006 | Volume: 305.5 |
Hydrophobic surface: 311.781 | Hydrophilic surface: 294.235 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 5 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |