Physical Properties | | | |
Molecular Weight: 375.469 g/mol | logS: -3.88284 | SlogP: 1.47607 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.164448 | Sterimol/B1: 3.99663 | Sterimol/B2: 5.00189 | Sterimol/B3: 5.74874 |
Sterimol/B4: 8.56607 | Sterimol/L: 15.7221 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 680.155 | Positive charged surface: 493.445 | Negative charged surface: 186.71 | Volume: 372 |
Hydrophobic surface: 481.851 | Hydrophilic surface: 198.304 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |