Physical Properties | | | |
Molecular Weight: 410.538 g/mol | logS: -5.56951 | SlogP: 4.0508 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.205514 | Sterimol/B1: 3.93611 | Sterimol/B2: 4.06536 | Sterimol/B3: 5.05443 |
Sterimol/B4: 8.89286 | Sterimol/L: 16.0676 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 643.377 | Positive charged surface: 378.913 | Negative charged surface: 264.465 | Volume: 397.125 |
Hydrophobic surface: 466.569 | Hydrophilic surface: 176.808 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |