Physical Properties | | | |
Molecular Weight: 386.448 g/mol | logS: -2.50669 | SlogP: 2.5447 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.109704 | Sterimol/B1: 2.19605 | Sterimol/B2: 3.39861 | Sterimol/B3: 4.73362 |
Sterimol/B4: 8.2583 | Sterimol/L: 16.8382 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 638.633 | Positive charged surface: 460.098 | Negative charged surface: 178.535 | Volume: 362.75 |
Hydrophobic surface: 499.435 | Hydrophilic surface: 139.198 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |