Physical Properties | | | |
Molecular Weight: 375.472 g/mol | logS: -2.87958 | SlogP: 1.5125 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0574051 | Sterimol/B1: 2.89363 | Sterimol/B2: 3.92626 | Sterimol/B3: 4.78553 |
Sterimol/B4: 6.28896 | Sterimol/L: 19.644 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 648.798 | Positive charged surface: 398.408 | Negative charged surface: 216.016 | Volume: 369.875 |
Hydrophobic surface: 516.905 | Hydrophilic surface: 131.893 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |