Physical Properties | | | |
Molecular Weight: 402.519 g/mol | logS: -4.34074 | SlogP: 3.11812 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0956188 | Sterimol/B1: 2.18209 | Sterimol/B2: 2.9949 | Sterimol/B3: 6.50806 |
Sterimol/B4: 8.50901 | Sterimol/L: 19.3483 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 707.909 | Positive charged surface: 464.792 | Negative charged surface: 243.117 | Volume: 387 |
Hydrophobic surface: 530.077 | Hydrophilic surface: 177.832 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |