Physical Properties | | | |
Molecular Weight: 365.366 g/mol | logS: -4.09678 | SlogP: 2.3626 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.209172 | Sterimol/B1: 3.92499 | Sterimol/B2: 4.69127 | Sterimol/B3: 5.15767 |
Sterimol/B4: 7.18977 | Sterimol/L: 14.8768 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 574.875 | Positive charged surface: 306.072 | Negative charged surface: 268.803 | Volume: 301.875 |
Hydrophobic surface: 357.14 | Hydrophilic surface: 217.735 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |