Physical Properties | | | |
Molecular Weight: 376.545 g/mol | logS: -3.2123 | SlogP: 2.6278 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.145276 | Sterimol/B1: 3.20963 | Sterimol/B2: 3.92541 | Sterimol/B3: 4.22352 |
Sterimol/B4: 10.2004 | Sterimol/L: 15.1769 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 633.138 | Positive charged surface: 513.58 | Negative charged surface: 119.559 | Volume: 383 |
Hydrophobic surface: 582.456 | Hydrophilic surface: 50.682 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |