Physical Properties | | | |
Molecular Weight: 407.491 g/mol | logS: -3.97763 | SlogP: 0.9986 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.117773 | Sterimol/B1: 3.06403 | Sterimol/B2: 3.301 | Sterimol/B3: 6.04715 |
Sterimol/B4: 6.98577 | Sterimol/L: 18.504 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 667.681 | Positive charged surface: 512.793 | Negative charged surface: 154.888 | Volume: 370.875 |
Hydrophobic surface: 484.132 | Hydrophilic surface: 183.549 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |