Physical Properties | | | |
Molecular Weight: 314.294 g/mol | logS: -1.49409 | SlogP: -0.88498 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.263353 | Sterimol/B1: 2.30407 | Sterimol/B2: 2.37417 | Sterimol/B3: 6.34898 |
Sterimol/B4: 7.18442 | Sterimol/L: 13.1981 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 514.506 | Positive charged surface: 304.698 | Negative charged surface: 209.809 | Volume: 267.875 |
Hydrophobic surface: 257.091 | Hydrophilic surface: 257.415 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 5 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 5 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |