Physical Properties | | | |
Molecular Weight: 406.869 g/mol | logS: -5.60508 | SlogP: 4.5075 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0569575 | Sterimol/B1: 2.48558 | Sterimol/B2: 3.18757 | Sterimol/B3: 4.53147 |
Sterimol/B4: 9.71146 | Sterimol/L: 17.9502 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 650.333 | Positive charged surface: 341.362 | Negative charged surface: 308.971 | Volume: 373.5 |
Hydrophobic surface: 513.445 | Hydrophilic surface: 136.888 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |