Physical Properties | | | |
Molecular Weight: 302.259 g/mol | logS: -1.03595 | SlogP: -2.5415 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.174 | Sterimol/B1: 3.17849 | Sterimol/B2: 4.23178 | Sterimol/B3: 4.27565 |
Sterimol/B4: 6.15076 | Sterimol/L: 11.9228 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 486.395 | Positive charged surface: 289.094 | Negative charged surface: 197.301 | Volume: 261.125 |
Hydrophobic surface: 306.712 | Hydrophilic surface: 179.683 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 2 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |