Physical Properties | | | |
Molecular Weight: 418.514 g/mol | logS: -4.51419 | SlogP: 2.49412 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.060795 | Sterimol/B1: 2.08168 | Sterimol/B2: 3.13764 | Sterimol/B3: 4.96642 |
Sterimol/B4: 11.6925 | Sterimol/L: 18.8895 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 712.712 | Positive charged surface: 489.64 | Negative charged surface: 223.072 | Volume: 390 |
Hydrophobic surface: 607.99 | Hydrophilic surface: 104.722 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |