Physical Properties | | | |
Molecular Weight: 418.514 g/mol | logS: -3.98431 | SlogP: 2.4477 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.085088 | Sterimol/B1: 2.39639 | Sterimol/B2: 2.44325 | Sterimol/B3: 5.71122 |
Sterimol/B4: 13.58 | Sterimol/L: 16.7038 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 692.334 | Positive charged surface: 473.522 | Negative charged surface: 218.812 | Volume: 391.5 |
Hydrophobic surface: 591.151 | Hydrophilic surface: 101.183 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |