Physical Properties | | | |
Molecular Weight: 458.966 g/mol | logS: -6.32136 | SlogP: 4.43512 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0828834 | Sterimol/B1: 2.11927 | Sterimol/B2: 2.69459 | Sterimol/B3: 5.42953 |
Sterimol/B4: 12.0164 | Sterimol/L: 17.4406 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 738.448 | Positive charged surface: 417.58 | Negative charged surface: 320.868 | Volume: 416.25 |
Hydrophobic surface: 651.37 | Hydrophilic surface: 87.078 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |