Physical Properties | | | |
Molecular Weight: 404.491 g/mol | logS: -4.87453 | SlogP: 2.69792 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.094152 | Sterimol/B1: 2.05588 | Sterimol/B2: 6.29913 | Sterimol/B3: 6.41299 |
Sterimol/B4: 6.58723 | Sterimol/L: 17.7419 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 671.665 | Positive charged surface: 447.957 | Negative charged surface: 223.708 | Volume: 372.875 |
Hydrophobic surface: 460.331 | Hydrophilic surface: 211.334 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |