Physical Properties | | | |
Molecular Weight: 444.556 g/mol | logS: -6.55145 | SlogP: 4.5029 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.151431 | Sterimol/B1: 3.43706 | Sterimol/B2: 3.68583 | Sterimol/B3: 6.0803 |
Sterimol/B4: 6.95085 | Sterimol/L: 16.9732 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 637.357 | Positive charged surface: 277.766 | Negative charged surface: 349.828 | Volume: 367.25 |
Hydrophobic surface: 481.17 | Hydrophilic surface: 156.187 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |