Physical Properties | | | |
Molecular Weight: 396.184 g/mol | logS: -4.11193 | SlogP: 2.8564 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0805733 | Sterimol/B1: 2.355 | Sterimol/B2: 2.98965 | Sterimol/B3: 4.3779 |
Sterimol/B4: 8.79372 | Sterimol/L: 12.99 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 540.32 | Positive charged surface: 260.571 | Negative charged surface: 279.749 | Volume: 286.375 |
Hydrophobic surface: 390.825 | Hydrophilic surface: 149.495 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |