Physical Properties | | | |
Molecular Weight: 313.306 g/mol | logS: -0.96988 | SlogP: -1.0209 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.112672 | Sterimol/B1: 3.31335 | Sterimol/B2: 3.73603 | Sterimol/B3: 5.27629 |
Sterimol/B4: 5.32738 | Sterimol/L: 14.9622 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 552.403 | Positive charged surface: 372.341 | Negative charged surface: 180.062 | Volume: 279 |
Hydrophobic surface: 322.594 | Hydrophilic surface: 229.809 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 5 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 5 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |