Physical Properties | | | |
Molecular Weight: 398.394 g/mol | logS: -6.3325 | SlogP: 2.7338 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0750927 | Sterimol/B1: 2.50341 | Sterimol/B2: 3.22513 | Sterimol/B3: 5.33732 |
Sterimol/B4: 7.24614 | Sterimol/L: 17.5299 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 656.035 | Positive charged surface: 318.886 | Negative charged surface: 337.149 | Volume: 367.25 |
Hydrophobic surface: 454.626 | Hydrophilic surface: 201.409 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 3 | Acid groups: 2 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |