Giorgio Cozza

 

 

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   Giorgio Cozza, Ph.D.

      Postdoctoral Associate

 

      Molecular Modeling Section

      Via Marzolo 5 - 35131- Padova (Italy)

      phone: +39 049 827 5801; fax: +39 049 827 5366

      email: giorgio.cozza@unipd.it; Skype user:

 

My CV (open pdf version):

Research Topics:

Design of Ser-Thr inhibitors in particular against CK2, CK1, Aurora A and MEK. Protein-Protein Interface Disruption.

 

 

Professional Skills:

Protein-based and ligand based drug design, Docking and virtual database screening, Molecular dynamics, Drug-likeness optimization, Pharmacophore search, Lead optimization, Homology modeling, Protein-Protein Docking and Bioinformatics.

 

 

Selected Publications:

Cozza G, Gianoncelli A, Montopoli M, Caparrotta L, Venerando A, Meggio F, Pinna LA, Zagotto G, Moro S. "Identification of novel protein kinase CK1 delta (CK1delta) inhibitors through structure-based virtual screening." Bioorg Med Chem Lett. 18, 5672-5675 (2008)

 

Cozza G, Moro S, Gotte G "Elucidation of the ribonuclease A aggregation process mediated by 3D domain swapping: A computational approach reveals possible new multimeric structures." Biopolymers 89, 26-39 (2007)

 

G. Cozza, P. Bonvini, E. Zorzi, G. Poletto, M.A. Pagano, S. Sarno, A. Donella-Deana, G. Zagotto, A. Rosolen, L.A. Pinna, F. Meggio, S. Moro “Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application.” J. Med. Chem. 49, 2363-2366 (2006)

 

 


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