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Protein-based and ligand based drug design, Docking and virtual database screening, Molecular dynamics, Drug-likeness optimization, Pharmacophore search, Lead optimization, Homology modeling, Protein-Protein Docking and Bioinformatics.
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Cozza G, Gianoncelli A, Montopoli M, Caparrotta L, Venerando A, Meggio
F, Pinna LA, Zagotto G, Moro S. "Identification of novel protein kinase
CK1 delta (CK1delta) inhibitors through structure-based virtual
screening." Bioorg Med Chem Lett. 18, 5672-5675 (2008)
Cozza G, Moro S, Gotte G "Elucidation of the ribonuclease A
aggregation process mediated by 3D domain swapping: A computational
approach reveals possible new multimeric structures." Biopolymers 89,
26-39 (2007)
G. Cozza, P. Bonvini, E. Zorzi, G. Poletto, M.A. Pagano, S. Sarno, A.
Donella-Deana, G. Zagotto, A. Rosolen, L.A. Pinna, F. Meggio, S. Moro
“Identification of ellagic acid as potent inhibitor of protein kinase
CK2: a successful example of a virtual screening application.” J. Med.
Chem. 49, 2363-2366 (2006)
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