Protein-based and ligand based drug design, Docking and virtual database screening, Molecular dynamics, Drug-likeness optimization, Pharmacophore search, Lead optimization, Homology modeling, Protein-Protein Docking and Bioinformatics.
Cozza G, Gianoncelli A, Montopoli M, Caparrotta L, Venerando A, Meggio
F, Pinna LA, Zagotto G, Moro S. "Identification of novel protein kinase
CK1 delta (CK1delta) inhibitors through structure-based virtual
screening." Bioorg Med Chem Lett. 18, 5672-5675 (2008)
Cozza G, Moro S, Gotte G "Elucidation of the ribonuclease A
aggregation process mediated by 3D domain swapping: A computational
approach reveals possible new multimeric structures." Biopolymers 89,
G. Cozza, P. Bonvini, E. Zorzi, G. Poletto, M.A. Pagano, S. Sarno, A.
Donella-Deana, G. Zagotto, A. Rosolen, L.A. Pinna, F. Meggio, S. Moro
“Identification of ellagic acid as potent inhibitor of protein kinase
CK2: a successful example of a virtual screening application.” J. Med.
Chem. 49, 2363-2366 (2006)