Physical Properties | | | |
Molecular Weight: 395.483 g/mol | logS: -5.16178 | SlogP: 4.36376 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0249042 | Sterimol/B1: 2.05187 | Sterimol/B2: 3.10885 | Sterimol/B3: 3.27568 |
Sterimol/B4: 10.1352 | Sterimol/L: 18.6998 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 667.263 | Positive charged surface: 425.722 | Negative charged surface: 241.541 | Volume: 370.5 |
Hydrophobic surface: 586.077 | Hydrophilic surface: 81.186 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |