Physical Properties | | | |
Molecular Weight: 282.304 g/mol | logS: -1.88344 | SlogP: -0.7297 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0764593 | Sterimol/B1: 2.48367 | Sterimol/B2: 3.37307 | Sterimol/B3: 4.18128 |
Sterimol/B4: 5.9543 | Sterimol/L: 14.1691 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 456.914 | Positive charged surface: 303.148 | Negative charged surface: 153.766 | Volume: 230.875 |
Hydrophobic surface: 164.383 | Hydrophilic surface: 292.531 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 5 | Acid groups: 1 | Basic groups: 0 |
Chiral centers: 4 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |