Physical Properties | | | |
Molecular Weight: 415.489 g/mol | logS: -6.27369 | SlogP: 4.91949 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0864772 | Sterimol/B1: 2.39849 | Sterimol/B2: 4.85685 | Sterimol/B3: 5.53606 |
Sterimol/B4: 7.91091 | Sterimol/L: 15.6248 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 693.663 | Positive charged surface: 405.877 | Negative charged surface: 277.943 | Volume: 409.125 |
Hydrophobic surface: 581.117 | Hydrophilic surface: 112.546 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |