Physical Properties | | | |
Molecular Weight: 459.615 g/mol | logS: -3.4921 | SlogP: 1.6719 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0420285 | Sterimol/B1: 3.47949 | Sterimol/B2: 3.5981 | Sterimol/B3: 5.90699 |
Sterimol/B4: 8.14852 | Sterimol/L: 20.5257 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 731.496 | Positive charged surface: 473.721 | Negative charged surface: 257.775 | Volume: 426.875 |
Hydrophobic surface: 606.7 | Hydrophilic surface: 124.796 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |