Physical Properties | | | |
Molecular Weight: 407.857 g/mol | logS: -5.87169 | SlogP: 4.30357 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0236365 | Sterimol/B1: 3.01871 | Sterimol/B2: 3.69205 | Sterimol/B3: 3.79686 |
Sterimol/B4: 7.89424 | Sterimol/L: 21.5615 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 667.512 | Positive charged surface: 388.137 | Negative charged surface: 279.375 | Volume: 365.75 |
Hydrophobic surface: 546.244 | Hydrophilic surface: 121.268 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |