Physical Properties | | | |
Molecular Weight: 419.525 g/mol | logS: -4.61406 | SlogP: 4.36302 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0925996 | Sterimol/B1: 2.09323 | Sterimol/B2: 3.43551 | Sterimol/B3: 4.89876 |
Sterimol/B4: 12.2547 | Sterimol/L: 17.5764 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 763.223 | Positive charged surface: 523.152 | Negative charged surface: 240.071 | Volume: 420.75 |
Hydrophobic surface: 719.976 | Hydrophilic surface: 43.247 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |